Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFB16634.1Metal-dependent hydrolase, beta-lactamase superfamily II. (289 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.743
SFA71253.1
Competence protein ComGB.
  
  
 0.626
SFB20674.1
DNA processing protein.
 
  
 0.623
SFB25009.1
Leader peptidase (prepilin peptidase) / N-methyltransferase.
  
  
 0.609
SFA69952.1
dCMP deaminase.
 
  
 0.597
SFA88148.1
Competence protein ComFC.
 
  
 0.577
SFB16649.1
Regulator of protease activity HflC, stomatin/prohibitin superfamily.
       0.569
SFB16666.1
Hypothetical protein.
       0.541
SFA71267.1
Competence-related pilin export protein ComGA.
  
  
 0.539
SFB19000.1
Spore cortex peptidoglycan biosynthesis regulator SpoVE; Belongs to the SEDS family.
 
     0.484
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
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