Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (360 aa)    
Predicted Functional Partners:
SFB18116.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
SFA72201.1
2-oxoisovalerate dehydrogenase E1 component beta subunit.
 0.998
SFB00365.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.998
SFB18131.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.994
SFB18147.1
Dihydrolipoamide dehydrogenase.
 
 
 0.990
SFA72218.1
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 
 0.980
SFB00377.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.973
SFA72167.1
Dihydrolipoamide dehydrogenase.
 
 
 0.943
SFB00389.1
Dihydrolipoamide dehydrogenase.
 
 
 0.942
SFA72126.1
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.921
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
Server load: medium (46%) [HD]