| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFA69165.1 | SFB31333.1 | SAMN04488072_10140 | SAMN04488072_11531 | Preprotein translocase subunit YajC. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.778 |
| SFA69165.1 | ffh | SAMN04488072_10140 | SAMN04488072_109143 | Preprotein translocase subunit YajC. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.912 |
| SFA69165.1 | secA | SAMN04488072_10140 | SAMN04488072_10365 | Preprotein translocase subunit YajC. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.935 |
| SFA69165.1 | secE | SAMN04488072_10140 | SAMN04488072_11717 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.946 |
| SFA69165.1 | secY | SAMN04488072_10140 | SAMN04488072_11753 | Preprotein translocase subunit YajC. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.939 |
| SFB31333.1 | SFA69165.1 | SAMN04488072_11531 | SAMN04488072_10140 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Preprotein translocase subunit YajC. | 0.778 |
| SFB31333.1 | SFB31439.1 | SAMN04488072_11531 | SAMN04488072_11540 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase-3 subunit delta'. | 0.881 |
| SFB31333.1 | SFB31451.1 | SAMN04488072_11531 | SAMN04488072_11541 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development). | 0.826 |
| SFB31333.1 | dnaX | SAMN04488072_11531 | SAMN04488072_11530 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.915 |
| SFB31333.1 | ffh | SAMN04488072_11531 | SAMN04488072_109143 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.683 |
| SFB31333.1 | recR | SAMN04488072_11531 | SAMN04488072_11532 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.994 |
| SFB31333.1 | secA | SAMN04488072_11531 | SAMN04488072_10365 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.670 |
| SFB31333.1 | secE | SAMN04488072_11531 | SAMN04488072_11717 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.625 |
| SFB31333.1 | secY | SAMN04488072_11531 | SAMN04488072_11753 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.630 |
| SFB31333.1 | tmk | SAMN04488072_11531 | SAMN04488072_11537 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.828 |
| SFB31439.1 | SFB31333.1 | SAMN04488072_11540 | SAMN04488072_11531 | DNA polymerase-3 subunit delta'. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.881 |
| SFB31439.1 | SFB31451.1 | SAMN04488072_11540 | SAMN04488072_11541 | DNA polymerase-3 subunit delta'. | Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development). | 0.969 |
| SFB31439.1 | dnaX | SAMN04488072_11540 | SAMN04488072_11530 | DNA polymerase-3 subunit delta'. | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.934 |
| SFB31439.1 | recR | SAMN04488072_11540 | SAMN04488072_11532 | DNA polymerase-3 subunit delta'. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.792 |
| SFB31439.1 | secA | SAMN04488072_11540 | SAMN04488072_10365 | DNA polymerase-3 subunit delta'. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.452 |