STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SET85128.1RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (259 aa)    
Predicted Functional Partners:
SET85098.1
Sporulation protein, YlmC/YmxH family.
 
     0.897
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.857
SET85185.1
Stage II sporulation protein GA (sporulation sigma-E factor processing peptidase); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
 
  
 0.845
SET25158.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
  
 0.818
SET89974.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
  
 0.810
SET85157.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
0.808
SET60534.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.807
SEU06500.1
AbrB family transcriptional regulator, stage V sporulation protein T.
  
   
 0.804
SET23743.1
Stage II sporulation protein R.
 
     0.799
SEU06339.1
Stage II sporulation protein E.
  
  
 0.780
Your Current Organism:
Salinibacillus kushneri
NCBI taxonomy Id: 237682
Other names: AS 1.3566, Bacillaceae bacterium 8-2, Bacillaceae bacterium W11-1, JCM 12390, S. kushneri, Salinibacillus kushneri Ren and Zhou 2005, strain 8-2
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