Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXP15039.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)    
Predicted Functional Partners:
KXP15037.1
Indolepyruvate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.864
KXP15038.1
Indolepyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.844
KXP14744.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.796
KXP03879.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.692
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.682
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.657
KXP12165.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
  0.653
KXP14228.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.649
aspA-2
Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.640
KXP06614.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.635
Your Current Organism:
Tsukamurella pseudospumae
NCBI taxonomy Id: 239498
Other names: DSM 44118, JCM 13375, JCM 15929 [[Tsukamurella sunchonensis]], KCTC 9827 [[Tsukamurella sunchonensis]], NCIMB 13963, NRRL B-24668 [[Tsukamurella sunchonensis]], T. pseudospumae, Tsukamurella pseudospumae Nam et al. 2004 emend. Teng et al. 2016, Tsukamurella sp. SCNU5, Tsukamurella sp. U5, Tsukamurella sunchonensis, Tsukamurella sunchonensis Seong et al. 2008, strain N1176, strain SCNU5 [[Tsukamurella sunchonensis]]
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