STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACP_0060Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (354 aa)    
Predicted Functional Partners:
ACP_0619
ATP-binding protein; Displays ATPase and GTPase activities.
  
  
 0.856
ACP_0059
RecF/RecN/SMC N-terminal domain protein; Identified by match to protein family HMM PF02463.
       0.645
ACP_0061
TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
       0.643
ACP_1247
Serine/threonine protein phosphatase, 2C family; Identified by similarity to GB:AAF81068.1; match to protein family HMM PF00481.
  
  
 0.598
ACP_1026
Serine/threonine protein phosphatase, 2C family; Identified by similarity to GB:AAF81068.1; match to protein family HMM PF00481.
  
  
 0.593
glmU
UDP-N-acetylglucosamine diphosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
   
 0.586
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
   
   0.489
ACP_1749
HAD-superfamily hydrolase, subfamily IIB; Identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR01484.
 
     0.465
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
     0.440
Your Current Organism:
Acidobacterium capsulatum
NCBI taxonomy Id: 240015
Other names: A. capsulatum ATCC 51196, Acidobacterium capsulatum ATCC 51196, Acidobacterium capsulatum str. ATCC 51196, Acidobacterium capsulatum strain ATCC 51196
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