node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP_0171 | adk | ACP_0171 | ACP_1430 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.912 |
ACP_0171 | coaBC | ACP_0171 | ACP_0613 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.911 |
ACP_0171 | coaE | ACP_0171 | ACP_1976 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.909 |
ACP_0171 | dcd | ACP_0171 | ACP_3335 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.916 |
ACP_0171 | hpt | ACP_0171 | ACP_0161 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.912 |
ACP_0171 | pncB | ACP_0171 | ACP_0986 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.916 |
ACP_0171 | ppGpp | ACP_0171 | ACP_2888 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.927 |
ACP_0171 | pyrG | ACP_0171 | ACP_2453 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.912 |
ACP_0171 | pyrR | ACP_0171 | ACP_2011 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.905 |
ACP_0171 | sthA | ACP_0171 | ACP_2380 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Soluble pyridine nucleotide transhydrogenase; Identified by similarity to SP:P27306; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. | 0.918 |
adk | ACP_0171 | ACP_1430 | ACP_0171 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.912 |
adk | coaE | ACP_1430 | ACP_1976 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.498 |
adk | hpt | ACP_1430 | ACP_0161 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.921 |
coaBC | ACP_0171 | ACP_0613 | ACP_0171 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.911 |
coaBC | coaE | ACP_0613 | ACP_1976 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.527 |
coaE | ACP_0171 | ACP_1976 | ACP_0171 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.909 |
coaE | adk | ACP_1976 | ACP_1430 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.498 |
coaE | coaBC | ACP_1976 | ACP_0613 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.527 |
dcd | ACP_0171 | ACP_3335 | ACP_0171 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.916 |
dcd | pyrG | ACP_3335 | ACP_2453 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.927 |