Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysK1Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)    
Predicted Functional Partners:
cysE
Serine O-acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172.
 
 0.935
ACP_1006
Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212.
 
 
 0.903
gltB
NADPH-dependent glutamate synthetase; Identified by similarity to SP:Q05755; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
     
 0.745
cysS
cysteine--tRNA ligase; Identified by match to protein family HMM PF01406; match to protein family HMM PF09190; match to protein family HMM PF09334; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.652
ACP_1008
Von Willebrand factor type A domain protein; Identified by match to protein family HMM PF00092; match to protein family HMM TIGR03436.
       0.558
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
    0.491
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.456
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.437
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.434
ACP_1011
Putative lipoprotein.
  
    0.413
Your Current Organism:
Acidobacterium capsulatum
NCBI taxonomy Id: 240015
Other names: A. capsulatum ATCC 51196, Acidobacterium capsulatum ATCC 51196, Acidobacterium capsulatum str. ATCC 51196, Acidobacterium capsulatum strain ATCC 51196
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.