| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACP_2016 | ACP_2017 | ACP_2016 | ACP_2017 | Oxidoreductase, FAD/FMN-binding; Identified by match to protein family HMM PF00724. | Transcription regulator protein; Identified by match to protein family HMM PF00376. | 0.548 |
| ACP_2017 | ACP_2016 | ACP_2017 | ACP_2016 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | Oxidoreductase, FAD/FMN-binding; Identified by match to protein family HMM PF00724. | 0.548 |
| ACP_2017 | ACP_2768 | ACP_2017 | ACP_2768 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | Lipoprotein releasing system, transmembrane protein, LolC/E family; Identified by match to protein family HMM PF02687. | 0.467 |
| ACP_2017 | dnaJ | ACP_2017 | ACP_2088 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.766 |
| ACP_2017 | dnaJ-2 | ACP_2017 | ACP_0801 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | Chaperone protein, DnaJ family; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.766 |
| ACP_2017 | hrcA | ACP_2017 | ACP_2086 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.465 |
| ACP_2017 | rpoA | ACP_2017 | ACP_1423 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.654 |
| ACP_2017 | rpoB | ACP_2017 | ACP_2928 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.789 |
| ACP_2017 | rpoC | ACP_2017 | ACP_2929 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.642 |
| ACP_2017 | rpoD | ACP_2017 | ACP_2445 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.712 |
| ACP_2017 | rpoZ | ACP_2017 | ACP_0615 | Transcription regulator protein; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.642 |
| ACP_2768 | ACP_2017 | ACP_2768 | ACP_2017 | Lipoprotein releasing system, transmembrane protein, LolC/E family; Identified by match to protein family HMM PF02687. | Transcription regulator protein; Identified by match to protein family HMM PF00376. | 0.467 |
| dnaJ | ACP_2017 | ACP_2088 | ACP_2017 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Transcription regulator protein; Identified by match to protein family HMM PF00376. | 0.766 |
| dnaJ | hrcA | ACP_2088 | ACP_2086 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.910 |
| dnaJ | rpoB | ACP_2088 | ACP_2928 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.473 |
| dnaJ-2 | ACP_2017 | ACP_0801 | ACP_2017 | Chaperone protein, DnaJ family; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Transcription regulator protein; Identified by match to protein family HMM PF00376. | 0.766 |
| dnaJ-2 | hrcA | ACP_0801 | ACP_2086 | Chaperone protein, DnaJ family; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.811 |
| hrcA | ACP_2017 | ACP_2086 | ACP_2017 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Transcription regulator protein; Identified by match to protein family HMM PF00376. | 0.465 |
| hrcA | dnaJ | ACP_2086 | ACP_2088 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.910 |
| hrcA | dnaJ-2 | ACP_2086 | ACP_0801 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Chaperone protein, DnaJ family; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.811 |