node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP_1768 | aroC | ACP_1768 | ACP_3127 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.984 |
ACP_1768 | aroD | ACP_1768 | ACP_2227 | Chorismate mutase; Identified by match to protein family HMM PF01817. | 3-dehydroquinate dehydratase, type I domain/shikimate 5-dehydrogenase domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family. | 0.545 |
ACP_1768 | trpA | ACP_1768 | ACP_1769 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.661 |
ACP_1768 | trpB | ACP_1768 | ACP_1770 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.661 |
ACP_1768 | trpC | ACP_1768 | ACP_1772 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.656 |
ACP_1768 | trpD | ACP_1768 | ACP_2598 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.401 |
ACP_1768 | trpE | ACP_1768 | ACP_2882 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.937 |
ACP_1768 | trpF | ACP_1768 | ACP_1771 | Chorismate mutase; Identified by match to protein family HMM PF01817. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.632 |
ACP_1768 | trpG | ACP_1768 | ACP_2879 | Chorismate mutase; Identified by match to protein family HMM PF01817. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.873 |
ACP_2878 | trpG | ACP_2878 | ACP_2879 | Hypothetical protein; Identified by glimmer; putative. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.799 |
aroC | ACP_1768 | ACP_3127 | ACP_1768 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; Identified by match to protein family HMM PF01817. | 0.984 |
aroC | aroD | ACP_3127 | ACP_2227 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-dehydroquinate dehydratase, type I domain/shikimate 5-dehydrogenase domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family. | 0.883 |
aroC | trpA | ACP_3127 | ACP_1769 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.814 |
aroC | trpB | ACP_3127 | ACP_1770 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.586 |
aroC | trpC | ACP_3127 | ACP_1772 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.498 |
aroC | trpD | ACP_3127 | ACP_2598 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.570 |
aroC | trpE | ACP_3127 | ACP_2882 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.958 |
aroC | trpF | ACP_3127 | ACP_1771 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.402 |
aroC | trpG | ACP_3127 | ACP_2879 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.894 |
aroD | ACP_1768 | ACP_2227 | ACP_1768 | 3-dehydroquinate dehydratase, type I domain/shikimate 5-dehydrogenase domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family. | Chorismate mutase; Identified by match to protein family HMM PF01817. | 0.545 |