STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D9C73_020847Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa)    
Predicted Functional Partners:
D9C73_001977
REST corepressor 3.
   
 0.979
D9C73_027323
REST corepressor 2.
   
 0.979
D9C73_001982
REST corepressor 3.
   
 0.979
D9C73_025496
Putative oxidoreductase GLYR1.
    
 
 0.959
D9C73_006994
PHD finger protein 21A BHC80a BRAF35-HDAC complex protein BHC80.
    
 0.956
D9C73_006996
PHD finger protein 21A BHC80a BRAF35-HDAC complex protein BHC80.
    
 0.956
D9C73_010720
Zinc finger protein 217.
    
 0.946
D9C73_015823
Zinc finger protein 516.
    
 0.939
D9C73_023274
Uncharacterized protein.
    
 0.939
D9C73_009450
Squalene synthase.
  
 
 0.934
Your Current Organism:
Collichthys lucidus
NCBI taxonomy Id: 240159
Other names: C. lucidus, Sciaena lucida, big head croaker
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.