STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (326 aa)    
Predicted Functional Partners:
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.996
CC1G_10037
Cytoplasmic protein.
    
 0.995
CC1G_06820
Uncharacterized protein.
   
 0.959
CC1G_01737
Phosphotyrosine protein phosphatase.
    
 0.869
CC1G_10288
Cytoplasmic protein.
   
 0.815
CC1G_01785
Integral membrane protein sed5.
   
 0.796
CC1G_13400
TPR_REGION domain-containing protein.
   
 0.754
CC1G_00017
Protein transporter SEC22; Belongs to the synaptobrevin family.
   
 
 0.736
CC1G_07282
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.689
CC1G_11759
TER94-PB.
   
 
 0.650
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 240176
Other names: C. cinerea okayama7#130, Coprinopsis cinerea okayama7#130, Coprinus cinereus okayama7#130
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