STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1502 aa)    
Predicted Functional Partners:
CC1G_05661
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.851
CC1G_13854
Proteasome subunit beta.
    
 
 0.796
CC1G_00724
Uncharacterized protein.
    
 0.791
CC1G_12185
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.782
CC1G_02270
Proteasome subunit alpha type.
    
 
 0.774
CC1G_05167
Proteasome endopeptidase complex; Belongs to the peptidase T1A family.
    
 
 0.774
CC1G_02904
Proteasome subunit beta.
    
 
 0.774
CC1G_14591
Proteasome endopeptidase complex; Belongs to the peptidase T1A family.
    
 
 0.774
CC1G_06872
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.708
CC1G_15504
Clathrin assembly protein AP47; Belongs to the adaptor complexes medium subunit family.
     
 0.660
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 240176
Other names: C. cinerea okayama7#130, Coprinopsis cinerea okayama7#130, Coprinus cinereus okayama7#130
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