| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ava_1171 | Ava_1347 | Ava_1171 | Ava_1347 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.930 |
| Ava_1347 | Ava_1171 | Ava_1347 | Ava_1171 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.930 |
| Ava_1347 | Ava_1668 | Ava_1347 | Ava_1668 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Serine O-acetyltransferase. | 0.953 |
| Ava_1347 | Ava_2127 | Ava_1347 | Ava_2127 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Aminotransferase. | 0.902 |
| Ava_1347 | Ava_3052 | Ava_1347 | Ava_3052 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.872 |
| Ava_1347 | Ava_3378 | Ava_1347 | Ava_3378 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Sulfide-quinone oxidoreductase. | 0.900 |
| Ava_1347 | Ava_3953 | Ava_1347 | Ava_3953 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Serine O-acetyltransferase. | 0.952 |
| Ava_1347 | Ava_5017 | Ava_1347 | Ava_5017 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Serine O-acetyltransferase. | 0.953 |
| Ava_1347 | Ava_5043 | Ava_1347 | Ava_5043 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.936 |
| Ava_1347 | ahcY | Ava_1347 | Ava_3963 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.845 |
| Ava_1347 | cysS | Ava_1347 | Ava_3718 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.830 |
| Ava_1668 | Ava_1347 | Ava_1668 | Ava_1347 | Serine O-acetyltransferase. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.953 |
| Ava_1668 | Ava_3953 | Ava_1668 | Ava_3953 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.902 |
| Ava_1668 | Ava_5017 | Ava_1668 | Ava_5017 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.901 |
| Ava_1668 | cysS | Ava_1668 | Ava_3718 | Serine O-acetyltransferase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.829 |
| Ava_2127 | Ava_1347 | Ava_2127 | Ava_1347 | Aminotransferase. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.902 |
| Ava_3052 | Ava_1347 | Ava_3052 | Ava_1347 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.872 |
| Ava_3052 | ahcY | Ava_3052 | Ava_3963 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.944 |
| Ava_3378 | Ava_1347 | Ava_3378 | Ava_1347 | Sulfide-quinone oxidoreductase. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.900 |
| Ava_3378 | Ava_5043 | Ava_3378 | Ava_5043 | Sulfide-quinone oxidoreductase. | Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.901 |