node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ava_1171 | Ava_4397 | Ava_1171 | Ava_4397 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Arogenate dehydrogenase (NADP). | 0.543 |
Ava_1171 | aroA | Ava_1171 | Ava_2259 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.796 |
Ava_1171 | panC/cmk | Ava_1171 | Ava_0964 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.419 |
Ava_1674 | aroA | Ava_1674 | Ava_2259 | Cytochrome bd plastoquinol oxidase subunit 1 apoprotein. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.660 |
Ava_3858 | Ava_4397 | Ava_3858 | Ava_4397 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | Arogenate dehydrogenase (NADP). | 0.575 |
Ava_3858 | aroA | Ava_3858 | Ava_2259 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.975 |
Ava_3858 | aroC | Ava_3858 | Ava_0589 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.907 |
Ava_3858 | aroE | Ava_3858 | Ava_3106 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.911 |
Ava_3858 | aroK | Ava_3858 | Ava_0553 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.973 |
Ava_3858 | hisS | Ava_3858 | Ava_2260 | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | histidyl-tRNA synthetase. | 0.444 |
Ava_4397 | Ava_1171 | Ava_4397 | Ava_1171 | Arogenate dehydrogenase (NADP). | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.543 |
Ava_4397 | Ava_3858 | Ava_4397 | Ava_3858 | Arogenate dehydrogenase (NADP). | 3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (By similarity); Belongs to the sugar phosphate cyclases superfamily. DDGS family. | 0.575 |
Ava_4397 | aroA | Ava_4397 | Ava_2259 | Arogenate dehydrogenase (NADP). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.973 |
Ava_4397 | aroB | Ava_4397 | Ava_4386 | Arogenate dehydrogenase (NADP). | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.723 |
Ava_4397 | aroC | Ava_4397 | Ava_0589 | Arogenate dehydrogenase (NADP). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.857 |
Ava_4397 | aroE | Ava_4397 | Ava_3106 | Arogenate dehydrogenase (NADP). | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.480 |
Ava_4397 | aroK | Ava_4397 | Ava_0553 | Arogenate dehydrogenase (NADP). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.509 |
Ava_4397 | panC/cmk | Ava_4397 | Ava_0964 | Arogenate dehydrogenase (NADP). | Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.474 |
aroA | Ava_1171 | Ava_2259 | Ava_1171 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.796 |
aroA | Ava_1674 | Ava_2259 | Ava_1674 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Cytochrome bd plastoquinol oxidase subunit 1 apoprotein. | 0.660 |