STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ava_3085RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Belongs to the sigma-70 factor family. (261 aa)    
Predicted Functional Partners:
Ava_0314
Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.882
rpoC2
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
    
 
 0.832
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.826
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.824
rpoC1
DNA-directed RNA polymerase gamma chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.806
Ava_0062
CheA Signal Transduction Histidine Kinases (STHK).
 
  
 0.706
Ava_3779
CheA Signal Transduction Histidine Kinases (STHK).
 
  
 0.686
rpoZ
RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.673
Ava_1850
Hypothetical protein.
  
  
 0.659
Ava_4696
GAF sensor hybrid histidine kinase.
  
  
 0.645
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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