STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ava_3474uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (517 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 0.999
Ava_1946
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.973
Ava_3297
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.973
Ava_2865
Precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase.
 
 
0.948
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.943
Ava_3075
uroporphyrinogen-III synthase.
 
 
0.940
Ava_2922
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
0.930
Ava_2866
Assimilatory nitrite reductase (ferredoxin) precursor; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.912
Ava_4539
Assimilatory nitrite reductase (ferredoxin) precursor; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.884
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.878
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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