STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ava_4606Hydrogenase expression/formation protein HypE. (367 aa)    
Predicted Functional Partners:
Ava_4604
Hydrogenase formation HypD protein.
 
 
 0.998
Ava_4603
Hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.995
Ava_4602
Hydrogenase maturation protein HypF.
 
 
 0.994
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.958
Ava_4608
Hydrogenase accessory protein HypB.
 
  
 0.956
Ava_4595
Nickel-dependent hydrogenase, large subunit.
 
   
 0.814
Ava_4596
NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
   
 0.791
Ava_4661
NAD(P)-dependent nickel-iron dehydrogenase catalytic subunit.
 
   
 0.709
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
  0.546
Ava_4659
NAD(P)-dependent nickel-iron dehydrogenase subunit HoxY.
 
   
 0.527
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.