| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ava_1171 | Ava_3052 | Ava_1171 | Ava_3052 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.546 |
| Ava_1171 | Ava_5019 | Ava_1171 | Ava_5019 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.910 |
| Ava_1668 | Ava_3953 | Ava_1668 | Ava_3953 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.902 |
| Ava_1668 | Ava_4077 | Ava_1668 | Ava_4077 | Serine O-acetyltransferase. | O-acetylhomoserine sulfhydrolase. | 0.582 |
| Ava_1668 | Ava_5017 | Ava_1668 | Ava_5017 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.901 |
| Ava_1668 | Ava_5019 | Ava_1668 | Ava_5019 | Serine O-acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.966 |
| Ava_2127 | Ava_5019 | Ava_2127 | Ava_5019 | Aminotransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.901 |
| Ava_3052 | Ava_1171 | Ava_3052 | Ava_1171 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.546 |
| Ava_3052 | Ava_4077 | Ava_3052 | Ava_4077 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrolase. | 0.965 |
| Ava_3052 | Ava_5019 | Ava_3052 | Ava_5019 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.862 |
| Ava_3052 | ahcY | Ava_3052 | Ava_3963 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.964 |
| Ava_3378 | Ava_5019 | Ava_3378 | Ava_5019 | Sulfide-quinone oxidoreductase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.900 |
| Ava_3378 | Ava_5043 | Ava_3378 | Ava_5043 | Sulfide-quinone oxidoreductase. | Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.900 |
| Ava_3953 | Ava_1668 | Ava_3953 | Ava_1668 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.902 |
| Ava_3953 | Ava_4077 | Ava_3953 | Ava_4077 | Serine O-acetyltransferase. | O-acetylhomoserine sulfhydrolase. | 0.582 |
| Ava_3953 | Ava_5017 | Ava_3953 | Ava_5017 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.902 |
| Ava_3953 | Ava_5019 | Ava_3953 | Ava_5019 | Serine O-acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.964 |
| Ava_4077 | Ava_1668 | Ava_4077 | Ava_1668 | O-acetylhomoserine sulfhydrolase. | Serine O-acetyltransferase. | 0.582 |
| Ava_4077 | Ava_3052 | Ava_4077 | Ava_3052 | O-acetylhomoserine sulfhydrolase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.965 |
| Ava_4077 | Ava_3953 | Ava_4077 | Ava_3953 | O-acetylhomoserine sulfhydrolase. | Serine O-acetyltransferase. | 0.582 |
