| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDQ18425.1 | gcvT | BN982_00695 | BN982_00157 | Soluble hydrogenase 42 kDa subunit. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.811 |
| CDQ18425.1 | glyA | BN982_00695 | BN982_01107 | Soluble hydrogenase 42 kDa subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.862 |
| CDQ18425.1 | hom_2 | BN982_00695 | BN982_01185 | Soluble hydrogenase 42 kDa subunit. | Homoserine dehydrogenase. | 0.425 |
| CDQ18425.1 | pspA | BN982_00695 | BN982_01585 | Soluble hydrogenase 42 kDa subunit. | Phosphoserine phosphatase 1. | 0.696 |
| CDQ18425.1 | pspB | BN982_00695 | BN982_01874 | Soluble hydrogenase 42 kDa subunit. | Putative phosphoserine phosphatase 2. | 0.554 |
| CDQ18425.1 | pyk | BN982_00695 | BN982_00542 | Soluble hydrogenase 42 kDa subunit. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.795 |
| CDQ18425.1 | serA_1 | BN982_00695 | BN982_00007 | Soluble hydrogenase 42 kDa subunit. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.700 |
| CDQ18425.1 | yitJ_2 | BN982_00695 | BN982_03843 | Soluble hydrogenase 42 kDa subunit. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.516 |
| gcvT | CDQ18425.1 | BN982_00157 | BN982_00695 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Soluble hydrogenase 42 kDa subunit. | 0.811 |
| gcvT | glyA | BN982_00157 | BN982_01107 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
| gcvT | serA_1 | BN982_00157 | BN982_00007 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.566 |
| gcvT | yitJ_2 | BN982_00157 | BN982_03843 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.930 |
| glyA | CDQ18425.1 | BN982_01107 | BN982_00695 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Soluble hydrogenase 42 kDa subunit. | 0.862 |
| glyA | gcvT | BN982_01107 | BN982_00157 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.998 |
| glyA | hom_2 | BN982_01107 | BN982_01185 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Homoserine dehydrogenase. | 0.639 |
| glyA | pspA | BN982_01107 | BN982_01585 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase 1. | 0.787 |
| glyA | pspB | BN982_01107 | BN982_01874 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoserine phosphatase 2. | 0.600 |
| glyA | pyk | BN982_01107 | BN982_00542 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.683 |
| glyA | serA_1 | BN982_01107 | BN982_00007 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.580 |
| glyA | yitJ_2 | BN982_01107 | BN982_03843 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.942 |
