Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemL_1Glutamate-1-semialdehyde 2,1-aminomutase. (428 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.997
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.995
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.981
CDQ18189.1
uroporphyrinogen-III synthase.
 
 
 0.963
fabD
Malonyl CoA-acyl carrier protein transacylase.
    
 0.902
hemL1
Glutamate-1-semialdehyde 2,1-aminomutase 1.
     
  0.885
hemL_2
Glutamate-1-semialdehyde 2,1-aminomutase.
     
  0.885
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase.
 
      0.828
yclM
Aspartokinase 3; Belongs to the aspartokinase family.
   
 
  0.755
ccsA_1
Cytochrome c biogenesis protein CcsA.
  
  
 0.743
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
Server load: low (30%) [HD]