STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDQ18189.1uroporphyrinogen-III synthase. (257 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 0.997
sumT_1
Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.994
sumT_2
Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.994
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 
 0.970
hemL_1
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.951
ccsA_1
Cytochrome c biogenesis protein CcsA.
 
    0.928
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.860
hemL1
Glutamate-1-semialdehyde 2,1-aminomutase 1.
 
 
 0.844
sirC
Precorrin-2 dehydrogenase.
 
 
 0.837
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
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