STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CDQ19309.1Putative transcriptional regulator. (252 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.805
CDQ21067.1
Putative membrane-anchored protein.
  
     0.702
CDQ21068.1
Putative membrane-anchored protein.
  
     0.649
CDQ19025.1
PAP2 superfamily protein.
  
     0.584
CDQ21360.1
Germination protein, Ger(x)C family.
  
     0.565
CDQ21359.1
Spore germination protein (amino acid permease).
  
     0.564
pbuE_2
Purine efflux pump PbuE.
       0.534
CDQ18632.1
PAP2 superfamily protein.
  
     0.434
CDQ20574.1
Ribosomal-protein-alanine acetyltransferase.
  
     0.422
CDQ20343.1
Arginine transporter ATP-binding subunit.
  
     0.411
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
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