STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
mecAAdapter protein MecA 1; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. (232 aa)    
Predicted Functional Partners:
clpC
Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family.
    
 
 0.965
clpP_1
ATP-dependent Clp protease proteolytic subunit.
   
 
 0.794
clpP_2
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.794
CDQ21018.1
Competence protein.
 
     0.793
ytkD_2
Putative 8-oxo-dGTP diphosphatase YtkD; Belongs to the Nudix hydrolase family.
  
     0.693
CDQ18329.1
Virulence factor Mce family protein.
  
     0.665
CDQ21760.1
Initiation-control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.657
CDQ21016.1
Protein-disulfide isomerase.
  
  
 0.636
CDQ18334.1
Hypothetical protein; Belongs to the UPF0354 family.
  
     0.631
CDQ18233.1
Hypothetical protein.
  
     0.615
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.