| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDQ21049.1 | CDQ21050.1 | BN982_03412 | BN982_03413 | Phosphoglycolate phosphatase. | Hypothetical protein. | 0.487 |
| CDQ21049.1 | deoD | BN982_03412 | BN982_03674 | Phosphoglycolate phosphatase. | Purine nucleoside phosphorylase DeoD-type. | 0.508 |
| CDQ21049.1 | glyA | BN982_03412 | BN982_01107 | Phosphoglycolate phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.550 |
| CDQ21049.1 | guaA | BN982_03412 | BN982_02985 | Phosphoglycolate phosphatase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.786 |
| CDQ21049.1 | guaB | BN982_03412 | BN982_00652 | Phosphoglycolate phosphatase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.749 |
| CDQ21049.1 | nagC_1 | BN982_03412 | BN982_01292 | Phosphoglycolate phosphatase. | N-acetylglucosamine repressor. | 0.593 |
| CDQ21049.1 | pncB2 | BN982_03412 | BN982_00592 | Phosphoglycolate phosphatase. | Nicotinate phosphoribosyltransferase pncB2; Belongs to the NAPRTase family. | 0.518 |
| CDQ21049.1 | punA | BN982_03412 | BN982_01722 | Phosphoglycolate phosphatase. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.534 |
| CDQ21049.1 | ribD | BN982_03412 | BN982_01037 | Phosphoglycolate phosphatase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.828 |
| CDQ21049.1 | ribH | BN982_03412 | BN982_01040 | Phosphoglycolate phosphatase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.490 |
| CDQ21050.1 | CDQ21049.1 | BN982_03413 | BN982_03412 | Hypothetical protein. | Phosphoglycolate phosphatase. | 0.487 |
| deoD | CDQ21049.1 | BN982_03674 | BN982_03412 | Purine nucleoside phosphorylase DeoD-type. | Phosphoglycolate phosphatase. | 0.508 |
| deoD | guaB | BN982_03674 | BN982_00652 | Purine nucleoside phosphorylase DeoD-type. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.687 |
| deoD | pncB2 | BN982_03674 | BN982_00592 | Purine nucleoside phosphorylase DeoD-type. | Nicotinate phosphoribosyltransferase pncB2; Belongs to the NAPRTase family. | 0.922 |
| deoD | punA | BN982_03674 | BN982_01722 | Purine nucleoside phosphorylase DeoD-type. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.946 |
| glyA | CDQ21049.1 | BN982_01107 | BN982_03412 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoglycolate phosphatase. | 0.550 |
| glyA | guaA | BN982_01107 | BN982_02985 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.857 |
| glyA | guaB | BN982_01107 | BN982_00652 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.773 |
| glyA | ribD | BN982_01107 | BN982_01037 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.411 |
| guaA | CDQ21049.1 | BN982_02985 | BN982_03412 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Phosphoglycolate phosphatase. | 0.786 |