STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)    
Predicted Functional Partners:
frdA
Fumarate reductase flavoprotein subunit.
 
 0.994
frdB
Fumarate reductase iron-sulfur subunit.
  
 0.976
sdhC
Succinate dehydrogenase cytochrome b558 subunit.
   
 
 0.949
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.949
citZ
Citrate synthase 2; Belongs to the citrate synthase family.
   
 0.943
ldh_2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.927
maeB_1
NADP-dependent malic enzyme.
  
 
 0.925
mmgD
2-methylcitrate synthase; Belongs to the citrate synthase family.
   
 0.925
citB
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.919
rocF
Arginase; Belongs to the arginase family.
 
   
 0.917
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
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