STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDP45891.1Stage II sporulation protein AA (anti-sigma F factor antagonist); Belongs to the anti-sigma-factor antagonist family. (121 aa)    
Predicted Functional Partners:
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.997
SDP45837.1
RNA polymerase sporulation-specific sigma factor; Belongs to the sigma-70 factor family.
 
  
 0.977
rsbW
Serine/threonine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 
 0.897
SDP66266.1
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.793
SDP45748.1
Stage V sporulation protein AC.
 
   
 0.791
SDP45721.1
Stage V sporulation protein AD.
 
   
 0.788
SDP45688.1
Stage V sporulation protein AE.
 
     0.756
SDP22624.1
Serine/threonine-protein kinase RsbW.
  
 
 0.707
SDP66184.1
Serine/threonine-protein kinase RsbT.
  
 
 0.707
SDO94609.1
Stage IV sporulation protein A.
  
   
 0.677
Your Current Organism:
Halobacillus aidingensis
NCBI taxonomy Id: 240303
Other names: CGMCC 1.3703, H. aidingensis, Halobacillus aidingensis Liu et al. 2005, Halobacillus sp. AD-6, JCM 12771, strain AD-6
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