node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANZ64797.1 | ANZ65413.1 | AYR62_12390 | AYR62_07040 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.552 |
ANZ64797.1 | ANZ65431.1 | AYR62_12390 | AYR62_08335 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.618 |
ANZ64797.1 | mnmE | AYR62_12390 | AYR62_13985 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.538 |
ANZ64797.1 | obgE | AYR62_12390 | AYR62_04780 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.698 |
ANZ64797.1 | prfA | AYR62_12390 | AYR62_03790 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.584 |
ANZ64797.1 | rplM | AYR62_12390 | AYR62_08540 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.619 |
ANZ64797.1 | rplT | AYR62_12390 | AYR62_07130 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.623 |
ANZ64797.1 | rplU | AYR62_12390 | AYR62_06845 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.517 |
ANZ64797.1 | rplX | AYR62_12390 | AYR62_08640 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.568 |
ANZ64797.1 | rsfS | AYR62_12390 | AYR62_07100 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.547 |
ANZ65413.1 | ANZ64797.1 | AYR62_07040 | AYR62_12390 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.552 |
ANZ65413.1 | mnmE | AYR62_07040 | AYR62_13985 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.554 |
ANZ65413.1 | obgE | AYR62_07040 | AYR62_04780 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.446 |
ANZ65413.1 | rplM | AYR62_07040 | AYR62_08540 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.584 |
ANZ65413.1 | rplT | AYR62_07040 | AYR62_07130 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.554 |
ANZ65413.1 | rplU | AYR62_07040 | AYR62_06845 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.641 |
ANZ65413.1 | rplX | AYR62_07040 | AYR62_08640 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.608 |
ANZ65413.1 | rsfS | AYR62_07040 | AYR62_07100 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosome silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.712 |
ANZ65431.1 | ANZ64797.1 | AYR62_08335 | AYR62_12390 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.618 |
ANZ65431.1 | mnmE | AYR62_08335 | AYR62_13985 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.611 |