Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Neuregulin 1. (684 aa)    
Predicted Functional Partners:
ERBB4
Erb-b2 receptor tyrosine kinase 4.
    
 0.972
ENSACOP00000017695
annotation not available
    
 0.972
ENSACOP00000017742
annotation not available
    
 0.969
NRG4
Neuregulin 4.
    
 0.943
NRG3
Neuregulin 3.
     
 0.854
EGF
Epidermal growth factor.
    
 0.796
EREG
Epiregulin.
    
 0.723
NBR1
NBR1 autophagy cargo receptor.
    
 0.716
BTC
Betacellulin.
     
 0.662
ENSACOP00000009351
annotation not available
   
 
 0.639
Your Current Organism:
Amazona collaria
NCBI taxonomy Id: 241587
Other names: A. collaria, yellow-billed parrot
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