STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.972
ENSACOP00000012237
annotation not available
    
 0.966
ENSACOP00000012279
annotation not available
    
 0.966
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.782
ENSACOP00000015949
annotation not available
    
 0.750
GRAP2
GRB2 related adaptor protein 2.
    
 0.750
SPRY1
Sprouty RTK signaling antagonist 1.
  
0.746
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.743
PPP2CB
Protein phosphatase 2 catalytic subunit beta.
    
  0.712
PPP2CA
Protein phosphatase 2 catalytic subunit alpha.
    
  0.712
Your Current Organism:
Amazona collaria
NCBI taxonomy Id: 241587
Other names: A. collaria, yellow-billed parrot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.