STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.977
NGO_0018
Diguanylate cyclase.
     
  0.900
NGO_0365
XRE family transcriptional regulator.
     
  0.900
NGO_0676
Modification methylase.
     
  0.900
NGO_0873
Modification methylase.
     
  0.900
NGO_1209
Multidrug DMT transporter.
     
  0.900
NGO_1329
Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate.
     
 0.900
NGO_1795
Modification methylase.
     
  0.900
NGO_1894
5-methylcytosine methyltransferase.
     
  0.900
NGO_1991
Modification methylase.
     
  0.900
Your Current Organism:
Neisseria gonorrhoeae
NCBI taxonomy Id: 242231
Other names: N. gonorrhoeae FA 1090, Neisseria gonorrhoeae FA 1090
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