STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMW33668.1Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)    
Predicted Functional Partners:
AMW32928.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.556
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
    
  0.531
AMW32265.1
ATP-dependent Clp protease ATP-binding subunit ClpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
       0.525
AMW32135.1
Metallophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.518
AMW33263.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.514
AMW32104.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.506
AMW32264.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.506
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.496
AMW32105.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.484
AMW32835.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.445
Your Current Organism:
Fervidobacterium islandicum
NCBI taxonomy Id: 2423
Other names: ATCC 49647, DSM 5733, F. islandicum, Fervidibacterium islandicum, strain H-21, strain H21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.