STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmcALHypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (423 aa)    
Predicted Functional Partners:
AMW33570.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.805
AMW33516.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
polC
DNA polymerase III subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
    0.716
mfd
DEAD/DEAH box helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.654
AMW33573.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.598
AMW33574.1
Flagellar biosynthesis protein FlhB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.598
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
     0.546
AMW32970.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.524
acpS
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids and catalyzes the formation of 2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.
       0.490
AMW33815.1
Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.490
Your Current Organism:
Fervidobacterium islandicum
NCBI taxonomy Id: 2423
Other names: ATCC 49647, DSM 5733, F. islandicum, Fervidibacterium islandicum, strain H-21, strain H21
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