STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGG_02031Piwi domain-containing protein. (135 aa)    
Predicted Functional Partners:
MGG_07338
Nuclear envelope pore membrane protein POM 121.
   
 
  0.949
DCL2
ATP-dependent helicase DCL2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Belongs to the helicase family. Dicer subfamily.
   
 0.758
DCL1
ATP-dependent helicase DCL1; Dicer-like endonuclease which seems not to be involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway, contrary to its DCL2 counterpart; Belongs to the helicase family. Dicer subfamily.
   
 0.748
MGG_05995
Uncharacterized protein.
   
 0.664
MGG_09242
Uncharacterized protein.
    
 0.652
MGCH7_ch7g691
Importin N-terminal domain-containing protein.
    
 0.650
MGG_03157
Ribonuclease 3.
    
 0.617
MGG_09996
RNase III domain-containing protein.
    
 0.583
MGG_01524
60S ribosomal protein L3.
    
 0.544
DHH1
ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
   
 
 0.422
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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