STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGG_02405Uncharacterized protein. (542 aa)    
Predicted Functional Partners:
DHH1
ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
   
 
 0.997
MGG_06410
mRNA-decapping enzyme 2.
    
 
 0.893
MGG_05213
YjeF_N domain-containing protein.
    
 
 0.887
PAB1
Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...]
    
 
 0.839
MGG_05522
Uncharacterized protein.
    
 
 0.821
MGG_08693
Topoisomerase II.
   
 
 0.688
MGG_07633
NTP_transf_9 domain-containing protein.
    
 
 0.678
MGG_12403
5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.
    
 
 0.648
MGG_04647
Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.625
LSM1
U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
    
 
 0.603
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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