node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MGG_00053 | MGG_07174 | G4NET3 | G4MTL1 | NUC153 domain-containing protein. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.734 |
MGG_03979 | MGG_05481 | G4NGZ7 | G4MM53 | RNA polymerase II Elongator subunit. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.989 |
MGG_03979 | MGG_07081 | G4NGZ7 | G4MSN9 | RNA polymerase II Elongator subunit. | Elongator complex protein 4. | 0.970 |
MGG_03979 | MGG_07174 | G4NGZ7 | G4MTL1 | RNA polymerase II Elongator subunit. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.997 |
MGG_03979 | MGG_10424 | G4NGZ7 | G4NGB7 | RNA polymerase II Elongator subunit. | DPBB_1 domain-containing protein. | 0.751 |
MGG_03979 | MGG_11224 | G4NGZ7 | G4MYP4 | RNA polymerase II Elongator subunit. | Uncharacterized protein. | 0.799 |
MGG_03979 | MGG_12920 | G4NGZ7 | G4N519 | RNA polymerase II Elongator subunit. | Uncharacterized protein. | 0.840 |
MGG_03979 | MGG_14861 | G4NGZ7 | G4N694 | RNA polymerase II Elongator subunit. | Riboflavin aldehyde-forming enzyme. | 0.799 |
MGG_03979 | MGG_17701 | G4NGZ7 | G4NGR7 | RNA polymerase II Elongator subunit. | Uncharacterized protein. | 0.866 |
MGG_03979 | UBA4 | G4NGZ7 | A4RPM5 | RNA polymerase II Elongator subunit. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.422 |
MGG_05481 | MGG_03979 | G4MM53 | G4NGZ7 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | RNA polymerase II Elongator subunit. | 0.989 |
MGG_05481 | MGG_07081 | G4MM53 | G4MSN9 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Elongator complex protein 4. | 0.990 |
MGG_05481 | MGG_07174 | G4MM53 | G4MTL1 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.997 |
MGG_05481 | MGG_10424 | G4MM53 | G4NGB7 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | DPBB_1 domain-containing protein. | 0.777 |
MGG_05481 | MGG_11224 | G4MM53 | G4MYP4 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Uncharacterized protein. | 0.805 |
MGG_05481 | MGG_12920 | G4MM53 | G4N519 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Uncharacterized protein. | 0.892 |
MGG_05481 | MGG_14861 | G4MM53 | G4N694 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Riboflavin aldehyde-forming enzyme. | 0.805 |
MGG_05481 | MGG_17701 | G4MM53 | G4NGR7 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Uncharacterized protein. | 0.805 |
MGG_05481 | UBA4 | G4MM53 | A4RPM5 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.666 |
MGG_07081 | MGG_03979 | G4MSN9 | G4NGZ7 | Elongator complex protein 4. | RNA polymerase II Elongator subunit. | 0.970 |