STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGG_089753-hydroxy-3-methylglutaryl coenzyme A reductase. (1201 aa)    
Predicted Functional Partners:
MGG_01026
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.999
MGG_16219
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.990
MGG_06139
Squalene monooxygenase.
   
  
 0.926
MGG_06428
Uncharacterized protein.
   
 
 0.889
MGG_09205
E3 ubiquitin-protein ligase HRD1.
   
 
 0.888
MGG_09750
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
  
 0.813
MGG_07125
Isopentenyl-diphosphate Delta-isomerase.
 
  
 0.803
MGG_04628
Cytochrome P450 51; Belongs to the cytochrome P450 family.
   
  
 0.772
MGG_04432
Cytochrome P450 51; Belongs to the cytochrome P450 family.
   
  
 0.772
MGG_08654
Uncharacterized protein.
   
 
 0.762
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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