MGG_08095 protein (Pyricularia oryzae) - STRING interaction network

Nodes:

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Cooccurrence

Coexpression

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[Homology]

Score

MGG_08095

SWR1-complex protein 4. (656 aa)

Predicted Functional Partners:

MGG_06932

0.993

MGG_11256

0.993

MGG_05178

0.989

MGG_07142

0.987

MGG_00544

0.987

MGG_03958

0.985

MGG_09523

0.984

MGG_02183

0.978

MGG_03173

0.975

MGG_12827

0.962

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGG_00544	MGG_02183	G4NBG6	G4MP79	Uncharacterized protein.	Helicase swr-1.	0.835
MGG_00544	MGG_03173	G4NBG6	G4NAF3	Uncharacterized protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.759
MGG_00544	MGG_03958	G4NBG6	G4NH29	Uncharacterized protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.760
MGG_00544	MGG_05178	G4NBG6	G4N4Z9	Uncharacterized protein.	AF-9.	0.973
MGG_00544	MGG_06932	G4NBG6	G4MNE5	Uncharacterized protein.	Enhancer of polycomb-like protein.	0.992
MGG_00544	MGG_07142	G4NBG6	G4MT67	Uncharacterized protein.	Uncharacterized protein.	0.973
MGG_00544	MGG_08095	G4NBG6	G4MYA8	Uncharacterized protein.	SWR1-complex protein 4.	0.987
MGG_00544	MGG_09523	G4NBG6	G4N1E0	Uncharacterized protein.	Atypical/PIKK/TRRAP protein kinase; Belongs to the PI3/PI4-kinase family.	0.982
MGG_00544	MGG_11256	G4NBG6	G4MXK8	Uncharacterized protein.	Actl6a protein; Belongs to the actin family.	0.963
MGG_00544	MGG_12827	G4NBG6	G4N702	Uncharacterized protein.	YL1_C domain-containing protein.	0.808
MGG_02183	MGG_00544	G4MP79	G4NBG6	Helicase swr-1.	Uncharacterized protein.	0.835
MGG_02183	MGG_03173	G4MP79	G4NAF3	Helicase swr-1.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.996
MGG_02183	MGG_03958	G4MP79	G4NH29	Helicase swr-1.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.996
MGG_02183	MGG_05178	G4MP79	G4N4Z9	Helicase swr-1.	AF-9.	0.954
MGG_02183	MGG_06932	G4MP79	G4MNE5	Helicase swr-1.	Enhancer of polycomb-like protein.	0.743
MGG_02183	MGG_07142	G4MP79	G4MT67	Helicase swr-1.	Uncharacterized protein.	0.807
MGG_02183	MGG_08095	G4MP79	G4MYA8	Helicase swr-1.	SWR1-complex protein 4.	0.978
MGG_02183	MGG_09523	G4MP79	G4N1E0	Helicase swr-1.	Atypical/PIKK/TRRAP protein kinase; Belongs to the PI3/PI4-kinase family.	0.905
MGG_02183	MGG_11256	G4MP79	G4MXK8	Helicase swr-1.	Actl6a protein; Belongs to the actin family.	0.984
MGG_02183	MGG_12827	G4MP79	G4N702	Helicase swr-1.	YL1_C domain-containing protein.	0.969

page 1 of 6

Network Stats

number of nodes:

10

number of edges:

21

average node degree:

4.2

avg. local clustering coefficient:

0.873

expected number of edges:

9

PPI enrichment p-value:

0.000652

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0040019

Positive regulation of embryonic development

2 of 6

2.88

0.81

0.0391

GO:0045039

Protein insertion into mitochondrial inner membrane

2 of 8

2.76

0.8

0.0391

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005743

Mitochondrial inner membrane

4 of 419

1.34

0.72

0.0279

GO:0098798

Mitochondrial protein-containing complex

3 of 267

1.41

0.65

0.0463

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6513

Mixed, incl. Tim10-like, and Mitochondrial intermembrane space import and assembly protein 40

4 of 17

2.73

3.46

5.49e-07

CL:6519

TIM22 mitochondrial import inner membrane insertion complex, and Tim10-like

3 of 5

3.14

2.98

5.61e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1268020

Mitochondrial protein import

3 of 47

2.16

1.47

0.0019

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042719

Mitochondrial intermembrane space protein transporter complex

2 of 5

2.96

1.46

0.0028

GOCC:0098798

Mitochondrial protein complex

4 of 228

1.6

1.2

0.0028

GOCC:0005740

Mitochondrial envelope

4 of 383

1.38

1.05

0.0034

GOCC:0031967

Organelle envelope

5 of 547

1.32

1.03

0.0028

GOCC:0071013

Catalytic step 2 spliceosome

2 of 37

2.09

0.92

0.0215

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0811

Translocation

2 of 20

2.36

1.05

0.0132

KW-0496

Mitochondrion

3 of 160

1.63

0.94

0.0132

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF10312

Conserved mid region of cactin

2 of 2

3.36

1.51

0.0023

PF04621

PEA3 subfamily ETS-domain transcription factor N terminal domain

2 of 4

3.06

1.45

0.0029

PF02953

Tim10/DDP family zinc finger

2 of 6

2.88

1.39

0.0036

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR019134

Splicing factor Cactin, C-terminal

2 of 2

3.36

1.23

0.0073

IPR018816

Splicing factor cactin, central domain

2 of 2

3.36

1.23

0.0073

IPR006715

PEA3-type ETS-domain transcription factor, N-terminal

2 of 4

3.06

1.22

0.0073

IPR035427

Tim10-like domain superfamily

2 of 6

2.88

1.18

0.0085

IPR004217

Tim10-like

2 of 6

2.88

1.18

0.0085

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01050

Cactus-binding C-terminus of cactin protein

2 of 3

3.18

1.65

0.0013

SM00413

Erythroblast transformation specific domain

2 of 32

2.15

0.8

0.0372

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