STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xlr1Xylanolytic transcriptional activator xlnR homolog; Transcriptional activator of the pentose catabolic pathway (PCP). Involved in the induction of a variety of PCP enzymes during growth on D-xylose. Has no effect on cellulolytic and xylanolytic enzyme activities. (1009 aa)    
Predicted Functional Partners:
XYR1
NAD(P)H-dependent D-xylose reductase XYR1; Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
      
 0.588
aguA
Alpha-glucuronidase; Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan. Belongs to the glycosyl hydrolase 67 family.
      
 0.564
EGD1
Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the [...]
      
 0.538
ARA1
L-arabinose-responsive transcription regulator ARA1; Transcriptional activator of the arabinanolytic system. Involved in the regulation of extracellular arabinanolytic genes and in the regulation of the intracellular activities of L-arabinose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of L-arabinose.
      
 0.532
MGG_11201
DNA-binding protein creA.
    
 0.491
XYL1
Endo-1,4-beta-xylanase 1; Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Accounts for approximately 70 percent of the endoxylanase activity in the culture filtrate (By similarity). Belongs to the glycosyl hydrolase 11 (cellulase G) family.
    
 
 0.484
MGG_13218
Pyruvate formate lyase activating enzyme.
 
      0.469
MGG_12860
Xylulose kinase.
      
 0.431
XYL5
Endo-1,4-beta-xylanase 5; Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose; Belongs to the glycosyl hydrolase 10 (cellulase F) family.
    
 
 0.419
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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