node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHH1 | MGG_04647 | A4R715 | G4MT85 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | 0.801 |
DHH1 | MGG_05213 | A4R715 | G4N542 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | YjeF_N domain-containing protein. | 0.999 |
DHH1 | MGG_06400 | A4R715 | G4N7J4 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. | 0.453 |
DHH1 | MGG_06410 | A4R715 | G4N7I3 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | mRNA-decapping enzyme 2. | 0.965 |
DHH1 | MGG_09170 | A4R715 | G4MPB4 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | LsmAD domain-containing protein. | 0.939 |
DHH1 | PAB1 | A4R715 | A4QUF0 | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.845 |
MGG_00449 | MGG_04647 | G4NC31 | G4MT85 | Eukaryotic peptide chain release factor GTP-binding subunit. | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | 0.501 |
MGG_00449 | MGG_06400 | G4NC31 | G4N7J4 | Eukaryotic peptide chain release factor GTP-binding subunit. | Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. | 0.502 |
MGG_00449 | PAB1 | G4NC31 | A4QUF0 | Eukaryotic peptide chain release factor GTP-binding subunit. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.931 |
MGG_04647 | DHH1 | G4MT85 | A4R715 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.801 |
MGG_04647 | MGG_00449 | G4MT85 | G4NC31 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic peptide chain release factor GTP-binding subunit. | 0.501 |
MGG_04647 | MGG_05213 | G4MT85 | G4N542 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | YjeF_N domain-containing protein. | 0.602 |
MGG_04647 | MGG_06400 | G4MT85 | G4N7J4 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. | 0.658 |
MGG_04647 | MGG_06410 | G4MT85 | G4N7I3 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | mRNA-decapping enzyme 2. | 0.546 |
MGG_04647 | MGG_09170 | G4MT85 | G4MPB4 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | LsmAD domain-containing protein. | 0.513 |
MGG_04647 | PAB1 | G4MT85 | A4QUF0 | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.974 |
MGG_05213 | DHH1 | G4N542 | A4R715 | YjeF_N domain-containing protein. | ATP-dependent RNA helicase DHH1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.999 |
MGG_05213 | MGG_04647 | G4N542 | G4MT85 | YjeF_N domain-containing protein. | Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. | 0.602 |
MGG_05213 | MGG_06400 | G4N542 | G4N7J4 | YjeF_N domain-containing protein. | Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. | 0.436 |
MGG_05213 | MGG_06410 | G4N542 | G4N7I3 | YjeF_N domain-containing protein. | mRNA-decapping enzyme 2. | 0.998 |