STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGG_06396MIF4G domain-containing protein. (1419 aa)    
Predicted Functional Partners:
TIF1
ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
   
 0.991
MGG_04647
Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family.
   
 0.991
PAB1
Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...]
   
 0.918
MGG_08170
Translation initiation factor eIF4E3; Belongs to the eukaryotic initiation factor 4E family.
    
 0.915
MGG_12123
Cap binding protein.
   
 0.843
MGG_05264
Translation initiation factor 4B.
   
 0.827
MGG_06296
Nuclear cap-binding protein subunit 2.
    
 0.810
MGG_14971
Elongation factor 3.
   
 
 0.787
MGG_08866
Eukaryotic translation initiation factor 5.
   
 0.756
MGG_13200
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.699
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.