MGG_13573 protein (Pyricularia oryzae) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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MGG_13573

FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (491 aa)

Predicted Functional Partners:

CEF1

0.626

MGG_00544

0.605

MGG_08095

0.462

MGG_06932

0.427

MGG_04877

0.420

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEF1	MGG_13573	Q52G60	G4N8S6	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	0.626
MGG_00544	MGG_06932	G4NBG6	G4MNE5	Uncharacterized protein.	Enhancer of polycomb-like protein.	0.992
MGG_00544	MGG_08095	G4NBG6	G4MYA8	Uncharacterized protein.	SWR1-complex protein 4.	0.987
MGG_00544	MGG_13573	G4NBG6	G4N8S6	Uncharacterized protein.	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	0.605
MGG_04877	MGG_13573	G4N2P6	G4N8S6	Transcription initiation factor TFIID subunit 6.	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	0.420
MGG_06932	MGG_00544	G4MNE5	G4NBG6	Enhancer of polycomb-like protein.	Uncharacterized protein.	0.992
MGG_06932	MGG_08095	G4MNE5	G4MYA8	Enhancer of polycomb-like protein.	SWR1-complex protein 4.	0.993
MGG_06932	MGG_13573	G4MNE5	G4N8S6	Enhancer of polycomb-like protein.	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	0.427
MGG_08095	MGG_00544	G4MYA8	G4NBG6	SWR1-complex protein 4.	Uncharacterized protein.	0.987
MGG_08095	MGG_06932	G4MYA8	G4MNE5	SWR1-complex protein 4.	Enhancer of polycomb-like protein.	0.993
MGG_08095	MGG_13573	G4MYA8	G4N8S6	SWR1-complex protein 4.	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	0.462
MGG_13573	CEF1	G4N8S6	Q52G60	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	0.626
MGG_13573	MGG_00544	G4N8S6	G4NBG6	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	Uncharacterized protein.	0.605
MGG_13573	MGG_04877	G4N8S6	G4N2P6	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	Transcription initiation factor TFIID subunit 6.	0.420
MGG_13573	MGG_06932	G4N8S6	G4MNE5	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	Enhancer of polycomb-like protein.	0.427
MGG_13573	MGG_08095	G4N8S6	G4MYA8	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.	SWR1-complex protein 4.	0.462

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.941

expected number of edges:

16

PPI enrichment p-value:

2.03e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006796

Phosphate-containing compound metabolic process

9 of 236

1.01

1.17

2.57e-07

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 327

0.86

0.88

3.63e-06

GO:1901566

Organonitrogen compound biosynthetic process

9 of 407

0.77

0.72

2.10e-05

GO:0006139

Nucleobase-containing compound metabolic process

9 of 537

0.65

0.55

0.00022

GO:0034641

Cellular nitrogen compound metabolic process

10 of 707

0.57

0.49

0.00014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

8 of 9

2.37

6.45

1.76e-14

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 3

2.25

1.23

0.0050

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

8 of 9

2.37

6.71

3.72e-15

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 6

2.34

4.18

3.68e-09

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 3

2.42

2.56

1.40e-05

GO:0005886

Plasma membrane

8 of 491

0.64

0.51

0.00095

GO:0005622

Intracellular anatomical structure

10 of 1040

0.41

0.33

0.0029

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22479625

(2012) Comparative analysis of gene content evolution in phytoplasmas and mycoplasmas.

4 of 102

1.02

0.56

0.0355

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:249

ATP synthesis

8 of 8

2.42

6.65

1.05e-14

CL:84

Ribosome, and Ribonucleoside triphosphate biosynthetic process

10 of 91

1.46

2.77

5.39e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pth00190

Oxidative phosphorylation

9 of 19

2.1

6.04

8.55e-16

pth01100

Metabolic pathways

8 of 503

0.63

0.47

0.0041

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

8 of 10

2.33

6.39

1.27e-14

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.42

4.26

3.81e-09

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 5

2.2

2.13

7.39e-05

GOCC:0032991

Protein-containing complex

9 of 435

0.74

0.67

6.39e-05

GOCC:0005622

Intracellular

10 of 995

0.43

0.34

0.0039

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

8 of 8

2.42

6.87

3.09e-15

KW-0066

ATP synthesis

8 of 8

2.42

6.87

3.09e-15

KW-0139

CF(1)

5 of 5

2.42

4.29

3.15e-09

KW-0138

CF(0)

3 of 3

2.42

2.46

2.19e-05

KW-1003

Cell membrane

8 of 110

1.29

1.85

2.66e-08

(more ...)

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