node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MGG_00518 | MGG_00519 | G4NBP7 | G4NBP6 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Vezatin domain-containing protein. | 0.900 |
MGG_00518 | MGG_00685 | G4NBP7 | G4NAX8 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.914 |
MGG_00518 | MGG_00704 | G4NBP7 | G4NEZ2 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.964 |
MGG_00518 | MGG_00841 | G4NBP7 | G4NE19 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Exonuclease 1. | 0.908 |
MGG_00518 | MGG_00879 | G4NBP7 | G4NDR8 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). | 0.918 |
MGG_00518 | MGG_04466 | G4NBP7 | G4MKK0 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA mismatch repair protein mutS. | 0.851 |
MGG_00518 | MGG_04627 | G4NBP7 | G4MRP9 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA_mis_repair domain-containing protein. | 0.740 |
MGG_00518 | MGG_07121 | G4NBP7 | G4MT39 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA mismatch repair protein mutL. | 0.814 |
MGG_00518 | MGG_15760 | G4NBP7 | G4MV84 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uncharacterized protein. | 0.775 |
MGG_00518 | MSH3 | G4NBP7 | A4R0R0 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] | 0.840 |
MGG_00519 | MGG_00518 | G4NBP6 | G4NBP7 | Vezatin domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.900 |
MGG_00519 | MGG_00685 | G4NBP6 | G4NAX8 | Vezatin domain-containing protein. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.914 |
MGG_00519 | MGG_00704 | G4NBP6 | G4NEZ2 | Vezatin domain-containing protein. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.964 |
MGG_00519 | MGG_00841 | G4NBP6 | G4NE19 | Vezatin domain-containing protein. | Exonuclease 1. | 0.908 |
MGG_00519 | MGG_00879 | G4NBP6 | G4NDR8 | Vezatin domain-containing protein. | DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). | 0.918 |
MGG_00519 | MGG_04466 | G4NBP6 | G4MKK0 | Vezatin domain-containing protein. | DNA mismatch repair protein mutS. | 0.851 |
MGG_00519 | MGG_04627 | G4NBP6 | G4MRP9 | Vezatin domain-containing protein. | DNA_mis_repair domain-containing protein. | 0.740 |
MGG_00519 | MGG_07121 | G4NBP6 | G4MT39 | Vezatin domain-containing protein. | DNA mismatch repair protein mutL. | 0.814 |
MGG_00519 | MGG_15760 | G4NBP6 | G4MV84 | Vezatin domain-containing protein. | Uncharacterized protein. | 0.775 |
MGG_00519 | MSH3 | G4NBP6 | A4R0R0 | Vezatin domain-containing protein. | DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] | 0.840 |