STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.995
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.984
aroE
Shikimate 5-dehydrogenase; Similar to GB:X57766, SP:P24347, PID:456257, and PID:987949; identified by sequence similarity; putative.
 
 
 0.981
PG_0885
Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; Similar to GB:Z21507, SP:P29692, and PID:38522; identified by sequence similarity; putative.
 
  
 0.883
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.829
PG_1525
Isochorismate synthase, putative; Similar to GB:X73039, SP:P35715, SP:P35717, SP:P48431, PID:312152, PID:854182, PID:938229, and PID:938234; identified by sequence similarity; putative.
 
   
 0.771
PG_1592
HDIG domain protein; Identified by match to TIGR protein family HMM TIGR01695.
       0.706
PG_1521
O-succinylbenzoic acid--CoA ligase; Similar to GB:L03728, SP:P22993, PID:147103, PID:152544, GB:X59798, GB:M73554, GB:S71637, SP:P24385, PID:179365, PID:181245, PID:307345, PID:312912, PID:35632, and PID:483601; identified by sequence similarity; putative.
      
 0.671
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
      
 0.631
ispE
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.622
Your Current Organism:
Porphyromonas gingivalis
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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