STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PG_1747Ribose 5-phosphate isomerase B, putative. (145 aa)    
Predicted Functional Partners:
tkt
Transketolase; Belongs to the transketolase family.
  
 
 0.973
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.934
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.929
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.924
PG_2010
Phosphomannomutase, putative.
     
 0.906
upp
Uracil phosphoribosyltransferase, putative; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.706
PG_0548
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein.
     
 0.630
PG_1684
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.565
PG_1746
ISPg2, transposase; Similar to GB:M32214, SP:P02905, GB:M83198, GB:X14825, PID:145174, PID:145890, PID:145892, PID:41362, PID:606195, GB:U00096, PID:1789653, GB:M32214, SP:P02905, GB:M83198, GB:X14825, PID:145174, PID:145890, PID:145892, PID:41362, PID:606195, GB:U00096, and PID:1789653; identified by sequence similarity; putative.
       0.479
pgi
Glucose-6-phosphate isomerase.
    
 0.478
Your Current Organism:
Porphyromonas gingivalis
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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