STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcdGlucose dehydrogenase Gcd; PMID: 8436115 PMID: 2803257 best DB hits: BLAST: gb:AAG18991.1; (AE004999) glucose dehydrogenase; Gcd; E=2e-27 pir:T44937; glucose 1-dehydrogenase (EC 1.1.1.47) [imported] -; E=1e-25 pir:S29788; glucose 1-dehydrogenase (EC 1.1.1.47) - Thermoplasma; E=3e-13 COG: VNG0446G; COG1063 Threonine dehydrogenase and related Zn-dependent; E=2e-28 YDL168w; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=0.003 XF1727; COG1063 Threonine dehydrogenase and related Zn-dependent; E=0.005 PFAM: PF00107; Zinc-binding dehydrogenases; E=3.1e-22. (371 aa)    
Predicted Functional Partners:
gdh
Probable glucose 1-dehydrogenase; PMID: 20479972 best DB hits: BLAST: embl:CAC11337.1; (AL445063) probable glucose 1-dehydrogenase; E=5e-28 ddbj:BAB20935.2; (D85817) ORF [Staphylococcus aureus]; E=2e-27 ddbj:BAB06210.1; (AP001515) 3-oxoacyl-(acyl-carrier protein); E=2e-27 COG: Ta0191; COG1028 Dehydrogenases with different specificities (related; E=5e-29 BS_ycdF; COG1028 Dehydrogenases with different specificities; E=3e-27 yohF; COG1028 Dehydrogenases with different specificities (related; E=5e-26 PFAM: PF02882; Tetrahydrofolate dehydrogenase/; E=0.28 PF00106; short chain dehydrogenase; [...]
  
 
  0.918
RB1022
Gluconolactonase; PMID: 1482681 best DB hits: BLAST: embl:CAB59581.1; (AL132662) possible gluconolactonase precursor; E=1e-19 pir:B82698; gluconolactonase precursor XF1297 [imported] - Xylella; E=2e-19 pir:A75539; probable gluconolactonase - Deinococcus radiodurans; E=2e-16 COG: XF1297; COG3386 Uncharacterized protein; E=2e-20.
   
 
  0.900
gnl
Gluconolactonase [precursor]; PMID: 1482681 best DB hits: BLAST: swissprot:Q01578; GNL_ZYMMO GLUCONOLACTONASE PRECURSOR; E=1e-54 gb:AAK03332.1; (AE006164) unknown [Pasteurella multocida]; E=1e-39 pir:B82698; gluconolactonase precursor XF1297 [imported] - Xylella; E=3e-39 COG: XF1297; COG3386 Uncharacterized protein; E=3e-40.
   
 
  0.900
RB3234
Possible gluconolactonase precursor; PMID: 1482681 best DB hits: BLAST: embl:CAB59581.1; (AL132662) possible gluconolactonase precursor; E=2e-26 pir:A75539; probable gluconolactonase - Deinococcus radiodurans; E=8e-20 pir:B82698; gluconolactonase precursor XF1297 [imported] - Xylella; E=8e-16 COG: DR0277; COG3386 Uncharacterized protein; E=8e-21.
   
 
  0.900
gnl-2
Gluconolactonase; PMID: 1482681 best DB hits: BLAST: embl:CAB59581.1; (AL132662) possible gluconolactonase precursor; E=2e-30 swissprot:Q01578; GNL_ZYMMO GLUCONOLACTONASE PRECURSOR; E=2e-19 pir:B82698; gluconolactonase precursor XF1297 [imported] - Xylella; E=3e-19 COG: XF1297; COG3386 Uncharacterized protein; E=3e-20.
   
 
  0.900
korA
2-oxoglutarate ferredoxin oxidoreductase alpha subunit; PMID: 11401501 best DB hits: BLAST: embl:CAC08296.1; (AL392148) putative oxidoreductase [Streptomyces; E=1e-165 embl:CAB60189.1; (AL132824) putative oxidoreductase alpha-subunit; E=1e-164 pir:F70864; probable oxidoreductase alpha subunit - Mycobacterium; E=1e-160 COG: Rv2455c_2; COG0674 Pyruvate:ferredoxin oxidoreductase and related; E=1e-106 Rv2455c_1; COG1014 Pyruvate:ferredoxin oxidoreductase and related; E=2e-46 BH2374_2; COG0674 Pyruvate:ferredoxin oxidoreductase and related; E=2e-40 PFAM: PF01855; Pyruvate flavodoxin/ferredo [...]
    
 0.847
RB2627
Glyceraldehyde 3-phosphate dehydrogenase; PMID: 8557349 best DB hits: BLAST: swissprot:O06822; G3P_MYCTU GLYCERALDEHYDE 3-PHOSPHATE; E=2e-99 swissprot:P46795; G3P_BORBU GLYCERALDEHYDE 3-PHOSPHATE; E=2e-99 swissprot:P46713; G3P_MYCLE GLYCERALDEHYDE 3-PHOSPHATE; E=6e-99 COG: Rv1436; COG0057 Glyceraldehyde-3-phosphate; E=1e-101 PFAM: PF01408; Oxidoreductase family, NAD-bindi; E=0.11 PF00044; Glyceraldehyde 3-phosphate dehyd; E=2.2e-118 PF02800; Glyceraldehyde 3-phosphate dehyd; E=5.5e-109; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.823
pgi
Glucose-6-phosphate isomerase; PMID: 2549364 best DB hits: BLAST: swissprot:P80860; G6PI_BACSU GLUCOSE-6-PHOSPHATE ISOMERASE (GPI); E=6e-53 ddbj:BAB07062.1; (AP001518) glucose-6-phosphate isomerase; E=4e-52 pir:S15937; glucose-6-phosphate isomerase (EC 5.3.1.9) - Bacillus; E=5e-52 COG: BS_pgi; COG0166 Glucose-6-phosphate isomerase; E=6e-54 PFAM: PF00342; Phosphoglucose isomerase; E=6.8e-31.
   
 0.815
ldh
L-lactate dehydrogenase; PMID: 3122782 PMID: 3118900 best DB hits: BLAST: swissprot:P00345; LDH_BACME L-LACTATE DEHYDROGENASE -----pir:; E=3e-49 swissprot:P20619; LDHX_BACPS L-LACTATE DEHYDROGENASE X -----; E=6e-47 swissprot:P16115; LDH_THEMA L-LACTATE DEHYDROGENASE ----- pir:; E=3e-46 COG: TM1867; COG0039 Malate/lactate dehydrogenases; E=2e-47 PFAM: PF00056; lactate/malate dehydrogenase, NA; E=6.7e-46 PF02866; lactate/malate dehydrogenase, al; E=2.4e-36; Belongs to the LDH/MDH superfamily.
   
 0.814
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.814
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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