Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB10049Probable alternative sigma factor AlgU; PMID: 8052622 best DB hits: BLAST: gb:AAF18265.1; U22895_1 (U22895) alternative sigma factor AlgU; E=2e-04 gb:AAF01335.1; AF190580_1 (AF190580) alternate sigma factor AlgT; E=8e-04 gb:AAC98488.1; (AF049107) putative ECF sigma factor RpoE1; E=0.001 COG: PA0762; COG1595 DNA-directed RNA polymerase specialized sigma; E=3e-04 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=3.1e-05 PF00140; Sigma-70 factor; E=0.6. (217 aa)    
Predicted Functional Partners:
RB10051
Hypothetical protein-transmembrane prediction.
     
 0.909
RB13241
Probable ECF-subfamily sigma factor; Best DB hits: BLAST: embl:CAC01348.1; (AL390975) putative ECF-subfamily sigma factor; E=2e-06 pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=7e-06 gb:AAC45221.1; (U87307) extracytoplasmic function alternative; E=7e-06 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=7e-07 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=1e-09.
  
   
 0.713
RB138
Hypothetical protein.
      
 0.618
RB10053
Hypothetical protein.
       0.581
RB10048
Sialic acid-specific 9-O-acetylesterase; PMID: 97078679 best DB hits: BLAST: embl:CAA67214.1; (X98625) sialic acid-specific 9-O-acetylesterase; E=1e-32 gb:AAB07813.1; (U40408) sialic-acid O-acetylesterase [Mus; E=2e-32 gb:AAD55976.1; (AF156856) cytosolic sialic acid; E=2e-29.
       0.566
sigW
Probable RNA polymerase sigma factor sigW; PMID: 9274029 best DB hits: BLAST: pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=6e-14 gb:AAC45221.1; (U87307) extracytoplasmic function alternative; E=2e-13 gb:AAC45219.1; (U87308) extracytoplasmic function alternative; E=5e-13 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=6e-15 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=2.1e-09.
  
     0.550
RB912
Similar to ECF-family RNA polymerase sigma factor; PMID: 8052622 best DB hits: BLAST: swissprot:P45215; YE59_HAEIN PROBABLE RNA POLYMERASE SIGMA FACTOR; E=0.28 embl:CAB55836.1; (AJ249581) Sig15 protein [Streptomyces; E=0.38 pir:F81002; probable sigma factor, NMB2144 [imported] - Neisseria; E=0.79 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=5.8e-10.
  
     0.474
rfaY
PMID: 8052622 best DB hits: BLAST: swissprot:P46358; RFAY_XANCP PROBABLE RNA POLYMERASE SIGMA FACTOR; E=5e-05 swissprot:P37978; CNRH_ALCEU RNA POLYMERASE SIGMA FACTOR CNRH; E=9e-04 pir:C69826; RNA polymerase ECF-type sigma factor homolog yhdM -; E=0.001 COG: BS_yhdM; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-04 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=4.8e-07.
  
     0.453
nccH
PMID: 7961470 best DB hits: BLAST: swissprot:Q44583; NCCH_ALCXX RNA POLYMERASE SIGMA FACTOR NCCH; E=6e-07 pir:H82073; RNA polymerase sigma-E factor VC2467 [imported] - Vibrio; E=3e-06 embl:CAB55345.1; (AJ010584) ECF sigma factor [Streptomyces; E=2e-05 COG: VC2467; COG1595 DNA-directed RNA polymerase specialized sigma; E=3e-07 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=9.7e-11.
  
     0.411
rpsH
RNA polymerase sigma-H factor; PMID: 8432708 best DB hits: BLAST: pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=1e-19 pir:S77368; transcription initiation factor sigma E slr1545 -; E=2e-19 gb:AAD42769.1; AF121849_1 (AF121849) SigG [Synechococcus sp. PCC; E=7e-18 COG: XF2239; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-20 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=1.5e-18 PF00140; Sigma-70 factor; E=0.55.
  
     0.404
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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