STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1005Conserved hypothetical protein-putative glycosyltransferase; PMID: 11016950 best DB hits: BLAST: gb:AAG18863.1; (AE004989) Vng0271c [Halobacterium sp. NRC-1]; E=7e-30 gb:AAG45169.1; AF317883_1 (AF317883) unknown [Synechococcus sp; E=8e-20 pir:T45180; hypothetical protein u1756l [imported] - Mycobacterium; E=0.026 COG: VNG0271C; COG0463 Glycosyltransferases involved in cell wall; E=7e-31. (478 aa)    
Predicted Functional Partners:
RB12343
Sucrose phosphorylase; PMID: 1368718 best DB hits: BLAST: swissprot:P76041; SUCP_ECOLI PUTATIVE SUCROSE PHOSPHORYLASE; E=1e-123 pir:H64879; probable membrane protein b1309 - Escherichia coli; E=1e-123 ddbj:BAA14878.1; (D90768) Sucrose phosphorylase (EC 2.4.1.7); E=1e-121 COG: ycjM; COG0366 Glycosidases; E=1e-124 PFAM: PF00128; Alpha amylase, catalytic domain; E=0.0025.
   
 0.985
RB12347
Similar to hydrolase; PMID: 7826004 best DB hits: BLAST: pir:G75522; hydrolase, CbbYCbbZ/GpH/YieH family - Deinococcus; E=0.045 swissprot:Q94915; REG2_DROME RHYTHMICALLY EXPRESSED GENE 2 PROTEIN; E=0.14 pir:E75169; hypothetical protein PAB2019 - Pyrococcus abyssi (strain; E=0.15 COG: DR0414; COG1011 Predicted hydrolases of the HAD superfamily; E=0.004 PFAM: PF00702; haloacid dehalogenase-like hydrolas; E=2e-07.
  
   
 0.717
RB5546
Hypothetical protein.
      
 0.680
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
   0.642
secD
Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.624
RB1009
Response regulator; PMID: 11123673 best DB hits: BLAST: pir:A75484; conserved hypothetical protein - Deinococcus radiodurans; E=2e-24 pir:D72252; conserved hypothetical protein - Thermotoga maritima; E=1e-23 embl:CAB89843.1; (AJ251547) response regulator [Xanthomonas; E=2e-23 COG: DR0719; COG2206 HD-GYP domain; E=2e-25 PFAM: PF01966; HD domain; E=7.2e-08.
   
   0.595
RB1010
Hypothetical protein.
       0.572
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
    0.547
recA
RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.471
RB1012
Hypothetical protein.
       0.448
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.