Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
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co-expression
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gene co-occurrence
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RB10065Conserved hypothetical protein-putative phosphohydrolase involved in signal transduction; Best DB hits: BLAST: ddbj:BAA82692.1; (AB013492) ORF14 [Bacillus halodurans] -----; E=4e-20 pir:D83132; hypothetical protein PA4108 [imported] - Pseudomonas; E=4e-17 pir:E71268; conserved hypothetical protein TP0912 - syphilis; E=4e-15 COG: BH0008; COG2206 HD-GYP domain; E=4e-21. (439 aa)    
Predicted Functional Partners:
RB3251
Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S76102; hypothetical protein slr0359 - Synechocystis sp. (strain; E=3e-99 pir:S76238; hypothetical protein sll0267 - Synechocystis sp. (strain; E=2e-89 pir:S77565; hypothetical protein slr2077 - Synechocystis sp. (strain; E=5e-88 COG: PA0575_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=1e-59 PFAM: PF00900; Ribosomal family S4e; E=0.72 PF00072; Response regulator receiver dom; E=3.8e-29 PF00785; PAC motif; E=0.054.
 
  
 0.829
RB3605
Conserved hypothetical protein-putative response regulator; PMID: 9384377 best DB hits: BLAST: pir:H83386; conserved hypothetical protein PA2072 [imported] -; E=1e-82 swissprot:P55552; Y4LL_RHISN HYPOTHETICAL 91.8 KD PROTEIN Y4LL; E=9e-82 pir:C83070; conserved hypothetical protein PA4601 [imported] -; E=7e-81 COG: PA2072_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=2e-52 yddU_3; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=1e-45 PA0575_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=2e-44 PFAM: PF00072; Response regulator receiver doma; E [...]
 
   
 0.758
RB1656
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:C83287; hypothetical protein PA2870 [imported] - Pseudomonas; E=4e-29 pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=1e-26 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=9e-24 COG: PA2870; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=4e-30 TM1594; COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); E=1e-22 PA0290_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=1e-22 PFAM: PF00989; PAS domain; E=2.5e-05 PF00990; GGDEF domain; E=5. [...]
 
 
 0.755
RB12571
GGDEF family protein; PMID: 10567266 best DB hits: BLAST: pir:E75266; GGDEF family protein - Deinococcus radiodurans (strain; E=2e-27 gb:AAA87378.1; (L42554) pleD gene product [Caulobacter; E=2e-25 gb:AAD28578.1; AF121341_2 (AF121341) putative response regulator; E=3e-25 COG: DR2498; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-28 TM1594; COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); E=7e-21 yddV_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=9e-21 PFAM: PF00897; Orbivirus inner capsid protein VP7; E=0.89 PF00498; FHA domain; E=1.3e-19 PF [...]
 
 
 0.741
RB12183
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:F82960; hypothetical protein PA5487 [imported] - Pseudomonas; E=8e-27 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=7e-22 pir:C83247; hypothetical protein PA3177 [imported] - Pseudomonas; E=2e-21 COG: PA5487; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=8e-28 PFAM: PF00990; GGDEF domain; E=2.8e-45.
  
 
 0.726
RB5964
Probable response regulatory protein; Best DB hits: BLAST: pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=1e-28 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=3e-26 pir:E72220; conserved hypothetical protein - Thermotoga maritima; E=1e-24 COG: aq_035_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=1e-29 TM1699_2; COG2206 HD-GYP domain; E=1e-24 aq_563_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-24 PFAM: PF01966; HD domain; E=6.6e-08 PF00989; PAS domain; E=0.032 PF00990; GGDEF domain; E=3.6e-53.
  
 
 0.725
RB1357
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=2e-26 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=5e-21 pir:G82209; GGDEF family protein VC1353 [imported] - Vibrio cholerae; E=8e-21 COG: aq_035_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-27 PFAM: PF00990; GGDEF domain; E=2.6e-46.
  
 
 0.720
RB12766
PMID: 11557134 best DB hits: BLAST: pir:C82181; conserved hypothetical protein VC1592 [imported] -; E=2e-15 pir:G70332; conserved hypothetical protein aq_367 - Aquifex aeolicus; E=6e-15 pir:D83238; hypothetical protein PA3258 [imported] - Pseudomonas; E=2e-13 COG: VC1592; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=1e-16 aq_367_3; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=6e-16 VC1641; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=2e-09 PFAM: PF00498; FHA domain; E=6.6e-15 PF00563; Domain of unknown function 2; E=3.1e-07.
 
  
 0.638
RB10308
Probable response regulatory protein; PMID: 9823893 PMID: 10984043 best DB hits: BLAST: pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=2e-21 pir:A82428; sensory boxGGDEF family protein VCA0697 [imported] -; E=6e-21 pir:E83183; probable two-component response regulator PA3702; E=1e-20 COG: VCA0697_3; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=6e-22 PFAM: PF00072; Response regulator receiver doma; E=5.4e-17 PF00990; GGDEF domain; E=7.2e-44.
  
   
 0.580
RB10062
Conserved hypothetical protein-putative oxidoreductase; Best DB hits: BLAST: pir:S76786; hypothetical protein - Synechocystis sp. (strain PCC; E=5e-83 gb:AAG57767.1; AE005495_2 (AE005495) orf, hypothetical protein; E=1e-80 swissprot:P37339; YGAF_ECOLI HYPOTHETICAL 48.6 KDA PROTEIN IN; E=2e-80 COG: sll1495; COG0579 Predicted dehydrogenase; E=5e-84 VCA0747; COG0578 Glycerol-3-phosphate dehydrogenase; E=0.005 PFAM: PF01224; FAD-dependent glycerol-3-phospha; E=0.37 PF00070; Pyridine nucleotide-disulphide o; E=0.038.
       0.527
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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