STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsAArylsulfatase A; PMID: 7910580 PMID: 1572648 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=4e-61 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=4e-61 pdb:1E2S; P Chain P, Crystal Structure Of An Arylsulfatase A; E=4e-60 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=5e-33 PFAM: PF00884; Sulfatase; E=3.7e-106. (489 aa)    
Predicted Functional Partners:
atsG
Probable sulfatase atsG; PMID: 10950929 PMID: 7910580 best DB hits: BLAST: pir:F70837; probable sulfatase (EC 3.1.6.-) atsG - Mycobacterium; E=9e-28 gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=5e-25 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=6e-25 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=8e-29 TM1703; COG1368 Phosphoglycerol transferase and related proteins,; E=0.008 PFAM: PF00884; Sulfatase; E=4e-22.
 
    
0.820
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
  
 
  0.709
nanH
Neuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038.
 
  
  0.650
trpC
Indole-3-glycerol phosphate synthase; PMID: 1896020 PMID: 7007653 PMID: 6355484 best DB hits: BLAST: swissprot:P26938; TRPC_AZOBR INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE; E=6e-55 swissprot:P94327; TRPC_BRAJA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE; E=3e-52 swissprot:Q9ZFA7; TRPC_RHOSH INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE; E=2e-51 COG: XF0213; COG0134 Indole-3-glycerol phosphate synthase; E=5e-51 PFAM: PF00218; Indole-3-glycerol phosphate synthase; E=2.6e-111; Belongs to the TrpC family.
       0.487
RB10115
Hypothetical protein.
       0.487
RB6738
Hypothetical protein.
 
      0.484
purH
Bifunctional purine biosynthesis protein purH; PMID: 3036807 best DB hits: BLAST: swissprot:P12048; PUR9_BACSU BIFUNCTIONAL PURINE BIOSYNTHESIS; E=1e-125 ddbj:BAB04352.1; (AP001509); E=1e-124 gb:AAF33520.1; (AF170176) Salmonella typhimurium; E=1e-118 COG: BS_purH; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only; E=1e-126 purH; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP; E=1e-119 HI0887; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only; E=1e-118 PFAM: PF02142; MGS-like domain; E=2.2e-46 PF01808; AICARFT/IMPCHase bienzyme; E=1.3e-113.
       0.457
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.